BAYLOR COLLEGE OF MEDICINE
Total received in grants · trailing 12 months
$2.0M
$0for every U.S. household÷ 131M U.S. households
In perspective
0.0%of all $162.9B in tracked grants
1separate grants, trailing 12 months
BAYLOR COLLEGE OF MEDICINE has received $2.0M across 1 federal grant of $1M or more on record.
Data as of July 24, 2026. Source: USAspending.gov, prime contract awards $1M+. Federal spending data lags and has known gaps. This is not a real-time or complete record.
Grants by agency
Where this recipient’s grant dollars come from.
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| Agency | Description | Amount |
|---|---|---|
| Department of Health and Human Services | ACQUISITION OF A 300 KEV CRYOEM/ET INSTRUMENT - WE PROPOSE TO PURCHASE A JEOL CRYOARM 300II CRYO-TRANSMISSION ELECTRON MICROSCOPE (TEM), WHICH WILL BE HOUSED IN THE CRYOEM/ET CORE AT BAYLOR COLLEGE OF MEDICINE. THIS INSTRUMENT IS A REPLACEMENT FOR A 20 YEAR OLD JEOL 3200 GOING OFF CONTRACT, WITH AN END-OF-LIFE DIRECT DETECTOR. CRITICALLY, THE RETIRING INSTRUMENT IS INCOMPATIBLE WITH THE SPECIMENS PRODUCED BY OUR THERMOFISHER AQUILOS 2 CRYO-FIB/SEM. OUR ONLY COMPATIBLE MICROSCOPE IS A THERMOFISHER GLACIOS WHICH OPERATES AT 200 KEV AND LACKS AN ENERGY FILTER, SEVERELY DEGRADING THE QUALITY OF THE TOMOGRAMS WE CAN ACQUIRE. OUR GLACIOS HAS ALSO PROVEN TO ACHIEVE ONLY ~2.5 Å RESOLUTION, WHICH IS ADEQUATE FOR SOME SINGLE PARTICLE PROJECTS AND FOR SCREENING, BUT IS NOT SUITABLE FOR FINAL COLLECTION OF LARGE DATA SETS. OUR CORE HAS SERVED OVER 40 DIFFERENT RESEARCH GROUPS IN THE LAST 3 YEARS PERFORMING A WIDE RANGE OF BIOLOGICAL RESEARCH INCLUDING VARIOUS CANCERS, VIRAL DISEASES, THE FUNCTION OF NEURONS AND STRUCTURES OF WIDE RANGING BIOMOLECULES. THE PROPOSED INSTRUMENT IS A SECOND GENERATION CRYOARM 300, WHICH CORRECTS ALL OF THE MINOR SHORTCOMINGS OF THE ORIGINAL INSTRUMENT, MAKING IT AN EXTREMELY ATTRACTIVE OPTION AT HALF THE PRICE OF A THERMOFISHER KRIOS. IN ADDITION TO HIGH QUALITY CRYOET DATA, IS ABLE TO COLLECT CRYOEM SINGLE PARTICLE DATA FOR STUDYING THE STRUCTURE AND DYNAMICS OF LARGE MACROMOLECULES TO NEAR-ATOMIC RESOLUTION, WITH HIGH THROUGHPUT. THERE IS ONLY ONE OTHER INSTRUMENT IN THE TEXAS MEDICAL CENTER, CAPABLE OF PERFORMING SOME, BUT NOT ALL, OF THE IMAGING WE WILL PERFORM ON THIS NEW INSTRUMENT. THAT KRIOS IS BEING USED AT VERY CLOSE TO CAPACITY (92% IN A RECENT YEAR) AND IT IS NOW 7 YEARS OLD. IT WAS DOWN SEVERAL MONTHS LAST YEAR, AND IS SUFFERING FROM A SPORADIC DETECTOR FAILURE REQUIRING A ~$1.5M REPLACEMENT. THE PROPOSED CRYOARM HAS DEMONSTRATED 1.2 Å RESOLUTION RECONSTRUCTIONS, LOADS CLIPPED GRIDS MAKING IT COMPATIBLE WITH THERMOFISHER INSTRUMENTS, AND HAS ALL OF THE OTHER FEATURES REQUIRED BY OUR USERS. ITS SOLE DISADVANTAGE IS THAT IT IS NOT AS THOROUGHLY AUTOMATED, REQUIRING A MORE SKILLED USER TO ACHIEVE EQUIVALENT THROUGHPUT. WE BELIEVE OUR IN-HOUSE EXPERTISE WITH JEOL INSTRUMENTS WILL ALLOW US TO ACHIEVE EXCELLENT PRODUCTIVITY WITH THIS INSTRUMENT IN ADDITION TO PROVIDING THE HIGHEST QUALITY DATA AND REDUCING WEEKS-LONG DELAYS IN OUR CURRENT WORKFLOWS TO HOURS. | $2,000,000 |